Table of Contents > Drug > Palonosetron Print

Palonosetron

Image

Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • U.S. Brand Names: Aloxi®
    • Mexican Brand Names: Onicit
    • Pharmacologic Category: Antiemetic;Selective 5-HT3 Receptor Antagonist

    Uses
    • This medicine is used to prevent nausea and vomiting from chemotherapy.
    • This medicine is used to prevent nausea and vomiting from surgery.
    • Palonosetron blocks chemicals in the stomach and brain that cause nausea and vomiting.

    Dosing

    How to take

    • This medicine is given as a shot into a vein.
    • To prevent nausea from chemotherapy, take 30 minutes before treatment or procedure.
    • To prevent nausea and vomiting from surgery, take just before procedure.

    Missed Dose

    • Call healthcare provider for appointment.

    Storage

    • This medicine will be given to you in a healthcare setting. You will not store it at home.

    Safety



    Warnings

    • This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.

    Avoid

    • If you have an allergy to palonosetron or any other part of this medicine.
    • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

    Precautions

    • If you have a heart condition called congenital QT syndrome, talk with healthcare provider.
    • If you have a low potassium or magnesium level, talk with healthcare provider.
    • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
    • Tell healthcare provider if you are pregnant or plan on getting pregnant.
    • Tell healthcare provider if you are breast-feeding.

    Side Effects

    • Headache.
    • Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
    • Irritation where the shot is given.
    • A faster, harmful heartbeat can rarely occur.

    Monitoring

    • Change in condition being treated. Is it better, worse, or about the same?
    • Follow up with healthcare provider.

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or emergency department immediately.
    • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
    • Significant change in thinking clearly and logically.
    • Severe headache.
    • Fast heartbeat.
    • Severe constipation.
    • Feeling extremely tired or weak.
    • Any rash.
    • No improvement in condition or feeling worse.

    General Statements

    • If you have a life-threatening allergy, wear allergy identification at all times.
    • Do not share your medicine with others and do not take anyone else's medicine.
    • Keep all medicine out of the reach of children and pets.
    • Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
    • Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
    • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

    Search Site

    Healthy Living Marketplace
    Olbas
    Carlson Labs
    Eden Foods
    Almased
    Bakery on Main
    Wakunaga of America