Table of Contents > Drug > Methotrimeprazine Print

Methotrimeprazine

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: Canada: Apo-Methoprazine®;Novo-Meprazine;Nozinan®;PMS-Methotrimeprazine
    • Mexican Brand Names: Sinogan
    • Pharmacologic Category: Analgesic, Nonopioid;Antimanic Agent;Antipsychotic Agent, Typical

    Uses
    • It is used to treat schizophrenia. It may take 6 weeks to see the full effect.
    • It is used to ease pain.
    • It is used to treat problems with how one acts.
    • It is used to treat sleep problems.
    • It is used to treat upset stomach and throwing up.
    • Methotrimeprazine lowers the feeling of pain and how one reacts to pain.
    • It affects the throwing up (vomiting) center in the brain.
    • It calms the brain.

    Dosing

    How to take

    • Oral:
    • Take with meals.
    • Keep a pain diary.
    • Shot:
    • It is given as a shot into a muscle, vein, or into the fatty part of the skin.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.

    Storage

    • Store at room temperature.
    • Protect tablets from water. Do not store in a bathroom or kitchen.
    • Shot:
    • This drug will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Warnings

    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.

    Avoid

    • If you have an allergy to methotrimeprazine, phenothiazines, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Bleeding problems or liver disease.

    Precautions

    • If you have high blood sugar (diabetes), talk with your doctor.
    • If you have heart disease, talk with your doctor.
    • If you have seizures, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • You may not be alert. Avoid driving and doing other tasks or actions until you see how this drug affects you.
    • Avoid beer, wine, mixed drinks, or other drugs and natural products that slow your actions.
    • Limit your use of caffeine (for example, tea, coffee, cola) and chocolate. Use with this drug may cause nervousness, shakiness, and a fast heartbeat.
    • Be careful in hot weather. Drink lots of fluids to stop fluid loss.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Headache.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
    • Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
    • Weight gain.
    • Change in sex ability. This most often goes back to normal.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad dizziness or passing out.
    • A fast heartbeat.
    • Trouble breathing.
    • Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life.
    • Change in thinking clearly and with logic.
    • Shakiness, trouble moving around, or stiffness.
    • Poor pain control.
    • Very upset stomach or throwing up.
    • Very hard stools (constipation).
    • Not able to pass urine.
    • Any bruising or bleeding.
    • Dark urine or yellow skin or eyes.
    • Feeling very tired or weak.
    • For women, if you get pregnant while taking this drug.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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