Table of Contents > Drug > Amifostine Print

Amifostine

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Ethyol®
    • Brand Names: Canada: Ethyol®
    • Mexican Brand Names: Ethyol
    • Pharmacologic Category: Adjuvant, Chemoprotective Agent (Cytoprotective);Antidote

    Uses
    • It is used to lower the side effects of some cancers or radiation.
    • Amifostine protects cells from the harmful effects of these therapies.

    Dosing

    How to take

    • It is given as a shot into a vein over a period of time.
    • It may be given as a shot into the fatty part of the skin.
    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.

    Missed Dose

    • Call your doctor for an office visit.

    Storage

    • This drug will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Avoid

    • If you have an allergy to amifostine, aminothiol compounds, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are breast-feeding.

    Precautions

    • If you have heart disease, talk with your doctor.
    • If you are taking drugs for high blood pressure, talk with your doctor. Your doctor may ask you to skip that drug the day before and on the morning of care.
    • If you have low calcium levels, talk with your doctor.
    • If you have had a stroke, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Low blood pressure.
    • Allergic side effects may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Trouble breathing.
    • Chest pain or pressure or a fast heartbeat.
    • Very bad dizziness or passing out.
    • Very upset stomach or throwing up.
    • Very bad skin irritation.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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