Table of Contents > Drug > Morphine (Systemic) Print

Morphine (Systemic)

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Astramorph®/PF;AVINza®;Duramorph;Infumorph 200;Infumorph 500;Kadian®;MS Contin®;Oramorph® SR
    • Brand Names: Canada: Doloral;Kadian®;M-Eslon®;M.O.S.-SR®;M.O.S.-Sulfate®;M.O.S.® 10;M.O.S.® 20;M.O.S.® 30;Morphine Extra Forte Injection;Morphine Forte Injection;Morphine HP®;Morphine LP® Epidural;Morphine SR;Morphine-EPD;MS Contin SRT;MS Contin®;MS-IR®;Novo-Morphine SR;PMS-Morphine Sulfate SR;ratio-Morphine;ratio-Morphine SR;Sandoz-Morphine SR;Statex®;Teva-Morphine SR
    • Pharmacologic Category: Analgesic, Opioid

    Uses
    • It is used to ease pain.
    • Morphine sulfate lowers the feeling of pain and how one reacts to pain.

    Dosing

    How to take

    • Take with or without food. Take with food if it causes an upset stomach.
    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
    • Long-acting products: Swallow whole. Do not chew, break, or crush.
    • Do not use long-acting products for fast pain relief or on an as needed basis.
    • You may sprinkle contents of Kadian® or Avinza® capsule on soft food or liquid. Do not chew.
    • There is a liquid (solution) if you cannot swallow pills.
    • Make sure you have the right liquid; there is more than one strength.
    • Measure liquid doses carefully. Use the measuring device that comes with this drug.
    • Those who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.
    • Use suppository rectally.
    • Keep a pain diary.
    • Shot:
    • It is given as a shot into a muscle, vein, or into the fatty part of the skin.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Many times this drug is taken on an as needed basis.

    Storage

    • Store at room temperature.
    • Protect from light.
    • Protect capsules and tablets from water. Do not store in a bathroom or kitchen.
    • Store suppositories in a refrigerator. Do not freeze.
    • Throw away any unused drug by flushing down a toilet or sink.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Shot:
    • The shot will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Warnings

    • Watch patients getting this drug for misuse, abuse, and addiction.
    • Do not take Avinza® with beer, wine, mixed drinks, or products that have alcohol in them. Very bad effects may happen.
    • You will be closely watched by your doctor while getting Duramorph®. Unsafe effects may happen.
    • Do not chew or crush long-acting capsules or tablets. Very bad effects may happen if you take chewed or crushed long-acting capsules or tablets. Do not use long-acting products for fast pain relief or on an as needed basis.
    • Keep the oral solution in a safe place away from children. If your child takes this drug, get help right away.
    • Oral solution: Please read the medication guide.

    Avoid

    • If you have an allergy to morphine sulfate or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Asthma, raised pressure in the brain, bowel block, or lung disease.

    Precautions

    • If you have been taking this drug for many weeks, talk with your doctor before stopping. You may want to slowly stop this drug.
    • This drug may be habit-forming with long-term use.
    • If you have a history of a drug or drinking problem, talk with your doctor.
    • If you have an enlarged prostate, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have seizures, talk with your doctor.
    • If you have thyroid disease, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • You may not be alert. Avoid driving and doing other tasks or actions until you see how this drug affects you.
    • Avoid beer, wine, mixed drinks, or other drugs and natural products that slow your actions.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
    • Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad dizziness or passing out.
    • Trouble breathing.
    • Change in thinking clearly and with logic.
    • Poor pain control.
    • Very upset stomach or throwing up.
    • Very hard stools (constipation).
    • Feeling very tired or weak.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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